Efficient synthesis of furo[2,3-d]pyrimidin-4(3H)-ones

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Highly efficient multicomponent Biginelli’s synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by Al-MCM-41 under solvent-free conditions

In this study, an efficient and green process for the synthesis of dihydropyrimidin-2(1H)-ones from aromatic benzaldehydes, ethyl acetoacetate and urea using Al-MCM-41 as heterogeneous catalyst and microreactor under solvent-free conditions has been developed. The advantages of this method are easy work-up procedure, regeneration of the catalyst, clean and neutral reaction conditions.

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Highly efficient multicomponent Biginelli’s synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by Al-MCM-41 under solvent-free conditions

In this study, an efficient and green process for the synthesis of dihydropyrimidin-2(1H)-ones from aromatic benzaldehydes, ethyl acetoacetate and urea using Al-MCM-41 as heterogeneous catalyst and microreactor under solvent-free conditions has been developed. The advantages of this method are easy work-up procedure, regeneration of the catalyst, clean and neutral reaction conditions.

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Chemistry of polyhalogenated nitrobutadienes, 14: Efficient synthesis of functionalized (Z)-2-allylidenethiazolidin-4-ones

The reaction of mercaptoacetic acid esters with pentachloro-2-nitro-1,3-butadiene (1) provides an appropriate precursor for the synthesis of special thiazolidin-4-ones. Applying different anilines as the second constituent for the requisite cyclization step, a series of (Z)-2-allylidenethiazolidin-4-ones was obtained in yields up to 81%. Some subsequent reactions have been examined too, such as...

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ژورنال

عنوان ژورنال: Arkivoc

سال: 2008

ISSN: 1551-7012

DOI: 10.3998/ark.5550190.0009.d18